M+2-dependent phosphatase 1 (MDP1)

Function

• Mg+2-dependent tyrosine phosphatase

Cofactor: Mg+2 (putative)

Inhibition:

• inhibited by vanadate, Zn+2, Ca+2 (weak)

Structure

belongs to the HAD-like hydrolase superfamily

Alternative splicing

named isoforms=3

More general terms

• tyrosine phosphatase (protein tyrosine phosphatate, PTP)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=145553
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:145553
• UniProt: http://www.uniprot.org/uniprot/Q86V88.html