acyl-protein thioesterase 2 (lysophospholipase 2, LPL-I, LYPLA2)

Function

• may hydrolyze fatty acids from S-acylated Cys in proteins such as trimeric G alpha proteins or HRAS
• as lysophospholipase activity

palmitoyl-protein + H2O <--> palmitate + protein

Structure

belongs to the AB hydrolase 2 family

Compartment

cytoplasm

More general terms

• thiol esterase or thioesterase
• lysophospholipase

Database

• UniProt: http://www.uniprot.org/uniprot/O95372.html