tripeptidyl peptidase 2 (tripeptidyl aminopeptidase, TPP2)

Function

• component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway
• may be able to complement inhibited 26S proteasome function (putative)
• release of an N-terminal tripeptide from a polypeptide

Structure

belongs to the peptidase S8 family

Compartment

cytoplasm

More general terms

• subtilase
• aminopeptidase

Database

• UniProt: http://www.uniprot.org/uniprot/P29144.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7174
• OMIM: https://mirror.omim.org/entry/190470