paired immunoglobulin-like type 2 receptor beta (activating receptor PILR-beta, cell surface receptor FDFACT, PILRB FDFACT, PP1551)

Function

• paired receptors consist of highly related activating & inhibitory receptors
• role in the regulation of the immune system
• PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface

Structure

• contains 1 Ig-like V-type domain (immunoglobulin-like)

Compartment

membrane

Alternative splicing

named isoforms=3

More general terms

• cell surface receptor

Additional terms

• paired immunoglobulin-like type 2 receptor alpha (inhibitory receptor PILR-alpha, cell surface receptor FDF03, PILRA)

Database

• OMIM: https://mirror.omim.org/entry/605342
• UniProt: http://www.uniprot.org/uniprot/Q9UKJ0.html