glutamate dehydrogenase 2 (GDH2, GLUD2)

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Function

  • important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission
L-glutamate + H2O + NAD+/NADP+
            <-->
2-oxoglutarate + NH3 + NADH/NADPH

Structure

Compartment

mitochondria matrix

Expression

More general terms

References

  1. Stryer Biochemistry WH Freeman & Co, New York, 1988 pg 502
  2. Principles of Biochemistry 6th ed., White, Handler, Smith, Hill, & Lehman (eds.) McGraw-Hill, NY 1978, pg 695
  3. UniProt http://www.uniprot.org/uniprot/P49448.html

Database