hairy/enhancer-of-split related with YRPW motif 1 (hairy & enhancer of split-related protein 1, HESR-1, cardiovascular helix-loop-helix factor 2, HES-related repressor protein 2, HERP2, HEY1, CHF2, HESR1)

Function

• DNA-binding protein
• efficient DNA binding requires dimerization with another bHLH protein

Structure

• contains 1 basic helix-loop-helix (bHLH) domain
• contains 1 Orange domain

Compartment

nucleus

Expression

• expressed in somitic mesoderm, central nervous system, kidney, heart, nasal epithelium, & limbs

More general terms

• hairy & enhancer of split (HES)

Database

• OMIM: https://mirror.omim.org/entry/602953
• UniProt: http://www.uniprot.org/uniprot/Q9Y5J3.html