T-box transcription factor TBX22; T-box protein 22 (TBX22, TBOX22)

Function

• probable transcriptional regulator involved in developmental processes
• major determinant crucial to palatogenesis

Structure

• contains 1 T-box DNA-binding domain

Compartment

nucleus (putative)

Alternative splicing

named isoforms=2

Expression

seems to be expressed at a low level

Pathology

• defects in TBX22 are the cause of X-linked cleft palate with ankyloglossia

More general terms

• T-box (TBX) protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=50945
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:50945
• OMIM: https://mirror.omim.org/entry/300307
• OMIM: https://mirror.omim.org/entry/303400
• UniProt: http://www.uniprot.org/uniprot/Q9Y458.html