T-box transcription factor TBX4; T-box protein 4 (TBX4)

Function

• role in the transcriptional regulation of genes required for mesoderm differentiation
• probably plays a role in limb pattern formation

Structure

• contains 1 T-box DNA-binding domain

Compartment

nucleus (putative)

Pathology

• defects in TBX4 are the cause of small patella syndrome

More general terms

• T-box (TBX) protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9496
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9496
• OMIM: https://mirror.omim.org/entry/147891
• OMIM: https://mirror.omim.org/entry/601719
• UniProt: http://www.uniprot.org/uniprot/P57082.html