T-box transcription factor TBX2; T-box protein 2 (TBX2)

Function

• role in transcriptional regulation of genes required for mesoderm differentiation
• probably plays a role in limb pattern formation

Structure

contains 1 T-box DNA-binding domain

Compartment

nucleus (putative)

Expression

• expressed primarily in adult in kidney, lung, & placenta
• weak expression in heart & ovary

More general terms

• T-box (TBX) protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6909
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6909
• OMIM: https://mirror.omim.org/entry/600747
• UniProt: http://www.uniprot.org/uniprot/Q13207.html