phosphatase 2 regulatory subunit A alpha (medium tumor antigen-associated 61 KDA protein, PPP2R1A)

Function

• PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit & a variable regulatory B subunit
• interacts with IPO9

Structure

• each HEAT repeat appears to consist of two alpha helices joined by a hydrophilic region, the intrarepeat loop
• the repeat units may be arranged laterally to form a rod-like structure

belongs to the phosphatase 2A regulatory subunit A family

contains 15 HEAT repeats

More general terms

• phosphatase 2 regulatory subunit A

Additional terms

• phosphatase-2A (ceramide-activated protein phosphatase)

Database

• UniProt: http://www.uniprot.org/uniprot/P30153.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5518
• OMIM: https://mirror.omim.org/entry/605983
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5518