StAR-related lipid transfer protein 9; START domain-containing protein 9; StARD9 (STARD9, KIAA1300)
Jump to navigation
Jump to search
Function
- microtubule-dependent motor protein required for spindle pole assembly during mitosis
- required to stabilize the pericentriolar material
Structure
- belongs to the kinesin-like protein family
- contains 1 FHA domain
- contains 1 kinesin-motor domain
- contains 1 START domain
Compartment
- cytoplasm, cytoskeleton
- centrosome, centriole
- nucleus
- localizes throughout the cytoplasm & nucleus during interphase
- localizes to the daughter centriole during mitosis
- disappears in cytokinesis
Alternative splicing
named isoforms=3
Expression
- expressed in the central nervous system, muscle cells (cardiac muscle & skeletal muscle), pancreas, prostate & lung