Zn+2 transporter ZIP14 (Zrt- & Irt-like protein 14, ZIP-14, solute carrier family 39 member 14, LIV-1 subfamily of ZIP Zn+2 transporter 4, LZT-Hs4, SLC39A14, KIAA0062, ZIP14)

Function

• may be able to transport iron
  • acts as a Zn+2-influx transporter

Structure

• homotrimer
• belongs to the ZIP transporter (TC 2.A.5) family

Compartment

• membrane
• localized to the plasma membrane
• also found colocalized with F-actin concentrated on lamellipodiae

Alternative splicing

named isoforms=2

Expression

• ubiquitously expressed
• expressed in liver, pancreas, fetal liver, thyroid, cardiac ventricles, left atrium & fetal heart > spleen, thymus, & peripheral blood leukocytes

More general terms

• solute carrier family 39 (SLC39, SLC39A)
• transmembrane 8e protein
• Zn+2 transporter

Database

• OMIM: https://mirror.omim.org/entry/608736
• UniProt: http://www.uniprot.org/uniprot/Q15043.html