phospholipid-transporting ATPase 5B; ATPase class 5 type 10B (ATP10B, ATPVB, KIAA0715)

Function

• role in the transport of phospholipids from the outer to the inner leaflet of various membranes & the maintenance of asymmetric distribution of phospholipids

ATP + H2O + phospholipid(In) = ADP + phosphate + phospholipid(out)

Structure

• belongs to the cation transport ATPase (P-type) (TC 3.A.3) family, type IV subfamily

Compartment

membrane

Alternative splicing

named isoforms=3; A, B, C

Expression

• expressed in brain
• low expression in testis

More general terms

• phospholipid-transporting ATPase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23120
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23120
• UniProt: http://www.uniprot.org/uniprot/O94823.html