phospholipid-transporting ATPase 1B; ATPase class 1 type 8A member 2; ML-1 (ATP8A2, ATPIB)

Function

• role in the transport of phospholipids from the outer to the inner leaflet of various membranes & the maintenance of asymmetric distribution of phospholipids

ATP + H2O + phospholipid(In) = ADP + phosphate + phospholipid(out)

Structure

• belongs to the cation transport ATPase (P-type) (TC 3.A.3) family, type IV subfamily

Compartment

membrane

Alternative splicing

named isoforms=2

More general terms

• phospholipid-transporting ATPase
• phosphoprotein
• membrane protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51761
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51761
• OMIM: https://mirror.omim.org/entry/605870
• UniProt: http://www.uniprot.org/uniprot/Q9NTI2.html