acyl-CoA-binding protein; ACBP; diazepam-binding inhibitor; DBI; endozepine; EP (DBI)

Function

• binds medium- & long-chain acyl-CoA esters with very high affinity
• intracellular carrier of acyl-CoA esters (putative)
• able to displace diazepam from benzodiazepine recognition site on the GABA type A receptor
• neuropeptide modulating action of GABA receptor (putative)

Structure

• monomer
• belongs to the ACBP family
• ccontains 1 ACB domain (acyl-CoA-binding domain)

Alternative splicing

named isoforms=2

More general terms

• acyl-CoA-binding domain-containing protein (ACBP family, ACBD)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1622
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1622
• OMIM: https://mirror.omim.org/entry/125950
• UniProt: http://www.uniprot.org/uniprot/P07108.html