ubiquitin-conjugating enzyme E2 U; ubiquitin carrier protein U; ubiquitin-protein ligase U (UBE2U)

Function

• catalyzes covalent attachment of ubiquitin to other proteins
  • ubiquitin conjugation, 2nd step

ubiquitin + protein-Lys  -->   protein-Lys-ubiquitin
         + ATP          <--    +  AMP + H2P2O7-2

Structure

belongs to the ubiquitin-conjugating enzyme family

Alternative splicing

named isoforms=2

More general terms

• ubiquitin-conjugating protein E2 (ubiquitin carrier protein)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=148581
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:148581
• UniProt: http://www.uniprot.org/uniprot/Q5VVX9.html