ubiquitin-conjugating enzyme E2 J1; non-canonical ubiquitin-conjugating enzyme 1; NCUBE-1; Yeast ubiquitin-conjugating enzyme UBC6 homolog E; HsUBC6e (UBE2J1, NCUBE1, CGI-76, HSPC153, HSPC205)
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Function
- catalyzes the covalent attachment of ubiquitin to other proteins
- seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum
- protein modification; protein ubiquitination
Structure
- belongs to the ubiquitin-conjugating enzyme family
Compartment
- endoplasmic reticulum membrane
- single-pass type IV membrane protein