transportin-3 (transportin-SR, TRN-SR, importin-12, TNPO3 IPO12)

Function

• role in nuclear protein import as nuclear transport receptor
• in vitro, mediates the nuclear import of splicing factor SR proteins SFRS1 & SFRS2, by recognizing phosphorylated RS domains
• interacts with phosphorylated SFRS1 & SFRS2
• interacts with NUP62

Compartment

cytoplasm, nucleus

Alternative splicing

named isoforms=4

More general terms

• transportin (TNPO)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9Y5L0.html