double C2-like domain-containing protein beta (Doc2-beta, DOC2B)

Function

• role inin constitutive membrane trafficking, including dynein-dependent intracellular vesicle transport (putative)
• in vitro, binds Ca+2 & phospholipids via C2 domain 1
• interacts with cytoplasmic dynein light chain TCTEL1/TCTEX1

Structure

• contains 2 C2 domains

Compartment

membrane, peripheral membrane protein

Expression

• widely expressed
• highest levels in brain & kidney

More general terms

• Ca+2 binding protein

Database

• OMIM: https://mirror.omim.org/entry/604568
• UniProt: http://www.uniprot.org/uniprot/Q14184.html