regucalcin; RC; senescence marker protein 30; SMP-30 (RGN, SMP30)

Function

• Ca+2-binding protein
• regulates Ca+2-dependent enzymatic activity in the liver & kidney

Structure

belongs to the SMP-30/CGR1 family

Compartment

cytoplasm (putative)

Alternative splicing

named isoforms=2

Pathology

• a decrease of RGN leads to the dysregulation of Ca+2 signaling in the aged liver (putative)

More general terms

• Ca+2 binding protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9104
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9104
• OMIM: https://mirror.omim.org/entry/300212
• UniProt: http://www.uniprot.org/uniprot/Q15493.html