collagen type-11

Function

• associated with type-9 collagen
• may play a role in fibrillogenesis by controlling lateral growth of collagen 2 fibrils

Structure

• trimers composed of three different chains: COL11A1, COL11A2, & COL11A3
• COL5A1 can also be found instead of COL11A3

Compartment

• secreted, extracellular space, extracellular matrix (putative)

Pathology

• defects associated with
  • collagenopathy type 2
  • collagenopathy type 11

More general terms

• collagen