plasmolipin; plasma membrane proteolipid (PLLP, PMLP, TM4SF11)

Function

• appears to be involved in myelination
• may also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent & K+-selective

Structure

• hexamer arranged as a trimer of two plasmolipin subunits
• belongs to the MAL family
• contains 1 MARVEL domain extending through all 4 transmembrane domains

Compartment

membrane

More general terms

• transmembrane 4 protein
• oligomerizing protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51090
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51090
• OMIM: https://mirror.omim.org/entry/600340
• UniProt: http://www.uniprot.org/uniprot/Q9Y342.html