choline-phosphate cytidylyltransferase B; CCT-beta; CTP:phosphocholine cytidylyltransferase B; CCT B; CT B; phosphorylcholine transferase B (PCYT1B, CCTB)

Function

• controls phosphatidylcholine synthesis
• phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2
• extensively phosphorylated
• the beta-1 isoform seems to be much less phosphorylated

CTP + choline phosphate = diphosphate + CDP-choline

Structure

belongs to the cytidylyltransferase family

Compartment

endoplasmic reticulum

Alternative splicing

named isoforms=2 or 3

Expression

• highly expressed in testis, placenta, brain, ovary & fetus

More general terms

• nucleotidyltransferase
• oligomerizing protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9468
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9468
• OMIM: https://mirror.omim.org/entry/604926
• UniProt: http://www.uniprot.org/uniprot/Q9Y5K3.html