aldehyde dehydrogenase 1 family, member A1 (ALDH1A1, aldehyde dehydrogenase 1, aldehyde dehydrogenase cytosolic, RalDH1, ALDH-E1, LDC, ALDH1, PUMB1)

Function

• binds free retinaldehyde & retinaldehyde bound to cellular retinol-binding protein
• can convert/oxidize retinaldehyde to retinoic acid
• retinoic acid biosynthesis

retinaldehyde + NAD+ + H2O <--> retinoate + NADH

Structure

• homotetramer
• belongs to the aldehyde dehydrogenase family

Compartment

cytoplasm

More general terms

• aldehyde dehydrogenase
• oligomerizing protein

Database

• UniProt: http://www.uniprot.org/uniprot/P00352.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:216
• OMIM: https://mirror.omim.org/entry/100640
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=216