cytochrome b-c1 complex subunit 2, mitochondrial; complex III subunit 2; core protein 2; ubiquinol-cytochrome-c reductase complex core protein 2 (UQCRC2)

Function

• component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), a component of the mitochondrial respiratory chain
• core protein 2 is required for the assembly of the complex
• does not seem to have a protease activity as it lack the Zn+2-binding site

Structure

• belongs to the peptidase M16 family, UQCRC2/QCR2 subfamily

Compartment

• mitochondrial inner membrane
• peripheral membrane, matrix side

More general terms

• protein subunit
• mitochondrial membrane protein
• phosphoprotein

Component of

• ubiquinol cytochrome c reductase; respiratory complex 3

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7385
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7385
• OMIM: https://mirror.omim.org/entry/191329
• UniProt: http://www.uniprot.org/uniprot/P22695.html