cystatin 11 (CST11, CST8L)

Function

• antibacterial activity against the Gram-negative bacteria E. coli
• may play a role in sperm maturation & fertilization

Structure

belongs to the cystatin family

Compartment

• nucleus, cytoplasm
• nuclear & cytoplasmic in the epididymis
• localized to the postacrosomal & tail regions of sperm
• probably localized to the outer surface of sperm

Alternative splicing

named isoforms=2

Expression

• detected in the epithelium & lumen of the epididymis, & in sperm (at protein level)

More general terms

• cystatin

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H112.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=140880