killer cell immunoglobulin-like receptor 2DL3; MHC class I NK cell receptor; natural killer-associated transcript 2; NKAT-2; NKAT2a; NKAT2b; p58 natural killer cell receptor clone CL-6; p58 NK receptor; p58.2 MHC class-I-specific NK receptor; killer inhibitory receptor cl 2-3; KIR-023GB; CD158 antigen-like family member B2; CD158b2 (KIR2DL3, CD158B2, KIRCL23, NKAT2)

Function

• receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 & HLA-Cw7)
• inhibits the activity of NK cells thus preventing cell lysis

Structure

• belongs to the immunoglobulin superfamily
• contains 2 Ig-like C2-type domain (immunoglobulin-like)

Compartment

cell membrane

Alternative splicing

named isoforms=2

More general terms

• CD158
• killer cell immunoglobulin like receptor 2DL (KIR2DL)
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3804
• OMIM: https://mirror.omim.org/entry/604938
• UniProt: http://www.uniprot.org/uniprot/P43628.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3804