flavoprotein monooxygenase 5; dimethylaniline monooxygenase 5 [N-oxide forming]; hepatic flavin-containing monooxygenase 5 (FMO5)

Function

• in contrast with other forms of FMO ,it does not seem to be a drug-metabolizing enzyme

N,N-dimethylaniline + NADPH + O2
       <-->
N,N-dimethylaniline N-oxide + NADP+ + H2O

Cofactor: FAD

Structure

belongs to the FMO family

Compartment

• microsome membrane
• endoplasmic reticulum membrane

Expression

expressed in fetal & adult liver

More general terms

• flavoprotein mixed function oxidase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2330
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2330
• OMIM: https://mirror.omim.org/entry/603957
• UniProt: http://www.uniprot.org/uniprot/P49326.html