phosphate carrier (phosphate transporter/translocase, PTP, solute carrier family 25 member 3, SLC25A3, PHC, OK/SW-cl48)
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Function
- transport of phosphate groups from the cytosol to the mitochondrial matrix
- phosphate is cotransported with H+
Structure
- belongs to the mitochondrial carrier family
- contains 3 solcar repeats
Compartment
- mitochondrial inner membrane
Alternative splicing
named isoforms=2
Pathology
- defects in SLC25A3 are a cause of mitochondrial phosphate carrier deficiency
More general terms
References
- ↑ Principles of Biochemistry 6th ed., White, Handler, Smith, Hill, & Lehman (eds.) McGraw-Hill, NY 1978, pg 345
- ↑ Molecular Cell Biology (2nd ed) Darnell J; Lodish H & Baltimore D (eds), Scientific American Books, WH Freeman, NY 1990, pg 602
- ↑ UniProt http://www.uniprot.org/uniprot/Q00325.html