Threonine synthase-like 2 (TSH2, THNSL2)

Function

• acts as a catabolic phospho-lyase on both gamma- & beta-phosphorylated substrates
• degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia & phosphate

Cofactor: pyridoxal phosphate (putative)

Structure

belongs to the serine/threonine dehydratase family

Alternative splicing

named isoforms=4

More general terms

• lyase

Database

• UniProt: http://www.uniprot.org/uniprot/Q86YJ6.html