di-N-acetylchitobiase (CTBS, CTB)

Function

• role in the degradation of asparagine-linked glycoproteins
• hydrolyzes N-acetyl-beta-D-glucosamine (1-4)N-acetyl- glucosamine chitobiose core from the reducing end of the bond
• requires prior cleavage by glycosylasparaginase

Structure

belongs to the glycosyl hydrolase 18 family

Compartment

lysosome

More general terms

• hydrolase
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1486
• OMIM: https://mirror.omim.org/entry/600873
• UniProt: http://www.uniprot.org/uniprot/Q01459.html