pyrroline-5-carboxylate reductase 3 (P5CR 3, P5C reductase 3, pyrroline-5-carboxylate reductase-like protein, PYCRL)

Function

• amino-acid biosynthesis; L-proline biosynthesis
• L-proline from L-glutamate 5-semialdehyde: step 1/1

L-proline + NAD+/NADP+ <--> 1-pyrroline-5-carboxylate + NADH/NADPH

Structure

• homodecamer; composed of 5 homodimers (putative)
• belongs to the pyrroline-5-carboxylate reductase family

More general terms

• oxidoreductase

Database

• UniProt: http://www.uniprot.org/uniprot/Q53H96.html