histatin-1; histidine-rich protein 1; post-PB protein; PPB; contains: histatin-2 (HTN1, HIS1)

Function

• histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle)
• histatins also exhibit antibacterial & antifungal activities
• histatin-2 may be a proteolytic product, or the non-phosphorylated form of histatin-1

Structure

belongs to the histatin/statherin family

Compartment

secreted

Expression

submandibular & parotid glands

More general terms

• histatin; histidine-rich protein; post PB protein (PPB)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3346
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3346
• OMIM: https://mirror.omim.org/entry/142701
• UniProt: http://www.uniprot.org/uniprot/P15515.html