preprotachykinin-B; preproneurokinin-B; tachykinin-3; contains: neurokinin-B; NKB; neuromedin-K (TAC3, NKNB, UNQ585/PRO1155)

Function

• tachykinin precursor

Compartment

secreted

Alternative splicing

named isoforms=3

Expression

• in pregnancy, expression confined to outer syncytiotrophoblast of placenta
• significant concentrations can be detected in plasma as early as week 9

Pathology

• plasma concentrations are grossly elevated in pregnancy- induced hypertension & pre-eclampsia

More general terms

• preprotachykinin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6866
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6866
• OMIM: https://mirror.omim.org/entry/162330
• UniProt: http://www.uniprot.org/uniprot/Q9UHF0.html