protachykinin-1; PPT; preprotachykinin A; contains: substance P; neurokinin A; NKA; neuromedin L; substance K; neuropeptide K; NPK; neuropeptide gamma; C-terminal-flanking peptide (TAC1, NKA, NKNA, TAC2)

Function

• tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators & secretagogues, & contract (directly or indirectly) many smooth muscles

Structure

belongs to the tachykinin family

Compartment

secreted

Alternative splicing

named isoforms=4; alpha, beta, gamma, delta

More general terms

• preprotachykinin

More specific terms

• protachykinin alpha
• protachykinin beta
• protachykinin gamma

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6863
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:6863
• OMIM: https://mirror.omim.org/entry/162320
• UniProt: http://www.uniprot.org/uniprot/P20366.html