dedicator of cytokinesis protein 5 (DOCK5)

Function

• guanine nucleotide exchange factor (GEF) for Rho & Rac

Structure

• the DHR-2 domain may mediate some GEF activity
• belongs to the DOCK family
• contains 1 DHR-1 domain
• contains 1 DHR-2 domain
• contains 1 SH3 domain

Compartment

cytoplasm (putative)

Alternative splicing

named isoforms=2

More general terms

• dedicator of cytokinesis protein (DOCK)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=80005
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:80005
• UniProt: http://www.uniprot.org/uniprot/Q9H7D0.html