calponin-3; calponin, acidic isoform (CNN3)
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Function
- thin filament-associated protein implicated in regulation & modulation of smooth muscle contraction
- capable of binding to actin, calmodulin, troponin C & tropomyosin
- interaction of calponin with actin inhibits actomyosin Mg-ATPase activity
Structure
- belongs to the calponin family
- contains 3 calponin-like repeats
- contains 1 CH (calponin-homology) domain
Expression
- expressed in smooth muscle & other tissues