glycophorin-C; PAS-2'; glycoprotein beta; GLPC; glycoconnectin; sialoglycoprotein D; glycophorin-D; GPD; CD236 (GYPC, GPC)
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Function
- minor sialoglycoprotein in human erythrocyte membranes
- role in regulating the stability of red cells
Structure
- the blood group Gerbich antigens & receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain
Compartment
- cell membrane
- linked to the membrane via Band 4.1
Alternative splicing
named isoforms=2 glycophorin C; glycophorin D
Expression
- glycophorin C is expressed in erythrocytes
- glycophorin D is ubiquitous
Pathology
- receptor for Plasmodium falciparum merozoites
Polymorphism
- GYPC is responsible for the Gerbich blood group system
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P04921.html
- ↑ BGMUT; Note: Blood group antigen gene mutation database http://www.ncbi.nlm.nih.gov/projects/mhc/xslcgi.fcgi?cmd=bgmut/systems_info&system=gerbich
- ↑ Wikipedia; Note: glycophorin C entry http://en.wikipedia.org/wiki/glycophorin_C
- ↑ SeattleSNPs http://pga.gs.washington.edu/data/gypc/