signal peptide peptidase-like 2A; SPP-like 2A; SPPL2a; intramembrane protease 3; IMP-3; presenilin-like protein 2 (SPPL2A, IMP3, PSL2, PSEC0147)

Function

• intramembrane protease
• ITM2B processing
• interacts with ITM2B

Structure

• belongs to the peptidase A22B family
• contains 1 PA (protease associated) domain

Compartment

membrane

More general terms

• presenilin-like protein
• transmembrane 9 protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=84888
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:84888
• OMIM: https://mirror.omim.org/entry/608238
• UniProt: http://www.uniprot.org/uniprot/Q8TCT8.html