transmembrane gamma-carboxyglutamic acid protein 2; proline-rich gamma-carboxyglutamic acid protein 2; proline-rich Gla protein 2 (PRRG2, PRGP2, TMG2)

Function

• Gla residues are produced after subsequent post-translational modifications of Glu by vitamin K-dependent gamma-carboxylase
• interacts with NEDD4 (putative)

Structure

• contains 1 Gla (gamma-carboxy-glutamate) domain

Compartment

• membrane; single-pass type 1 membrane protein

Expression

• highly expressed in thyroid

More general terms

• proline-rich gamma-carboxyglutamic acid protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5639
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5639
• OMIM: https://mirror.omim.org/entry/604429
• UniProt: http://www.uniprot.org/uniprot/O14669.html