phospholipid scramblase 2; PL scramblase 2; Ca+2-dependent phospholipid scramblase 2 (PLSCR2)

Function

• may facilitate ATP-independent bidirectional transbilayer migration of phospholipids upon binding Ca+2, resulting in a loss of phospholipid asymmetry in the plasma membrane

Cofactor: Ca+2 (putative)

Structure

• belongs to the phospholipid scramblase family

Compartment

• membrane; single-pass type 2 membrane protein (putative)

Expression

• expressed exclusively in testis

More general terms

• phospholipid scramblase
• testis-specific protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57047
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57047
• OMIM: https://mirror.omim.org/entry/607610
• UniProt: http://www.uniprot.org/uniprot/Q9NRY7.html