acetyl-coenzyme A synthetase, cytoplasmic (acetate-CoA ligase, acyl-activating enzyme, acetyl-CoA synthetase, ACS, AceCS, acyl-CoA synthetase short-chain family member 2, ACSS2, ACAS2)

Function

• activates acetate so that it can be used for lipid synthesis or for energy generation

ATP + acetate + CoA <--> AMP + diphosphate + acetyl-CoA

Structure

• monomer
• belongs to the ATP-dependent AMP-binding enzyme family

Compartment

cytoplasm

More general terms

• acyl coenzyme-A [CoA] synthetase or acyl coenzyme-A [CoA] ligase

Database

• OMIM: https://mirror.omim.org/entry/605832
• UniProt: http://www.uniprot.org/uniprot/Q9NR19.html