Inner membrane protein COX18, mitochondrial precursor (cytochrome c oxidase assembly protein 18, COX18Hs, COX18, OXA1L2)

Function

• required for the insertion of integral membrane proteins into the mitochondrial inner membrane
• essential for the activity & assembly of cytochrome c oxidase
• role in translocation & export of the C-terminal part of COX2 protein into mitochondrial intermembrane space

Structure

belongs to the OXA1/oxaA family

Compartment

mitochondrial inner membrane

Alternative splicing

named isoforms=4

More general terms

• mitochondrial membrane protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N8Q8.html