mitoferrin-1 (mitochondrial iron transporter 1, solute carrier family 25 member 37, mitochondrial solute carrier protein, SLC25A37, MFRN, MSCP, HT015)

Function

• mitochondrial iron transporter
• specifically mediates iron uptake in developing erythroid cells
• heme biosynthesis
  • iron delivered into mitochondria, presumably as Fe+2
  • delivered to ferrochelatase to catalyze Fe+2 incorporation into protoprophyrin IX to make heme

Compartment

mitochondrial inner membrane

More general terms

• mitochondrial membrane protein
• transmembrane 6 protein
• solute carrier family 25 (SLC25, SLC25A)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9NYZ2.html