matrilin-4 (MATN4)

Function

• major component of the extracellular matrix of cartilage
• interacts with COMP

Structure

• contains 4 EGF-like domains
• contains 2 VWFA domains

Compartment

secreted

Alternative splicing

• named isoforms=4
• additional isoforms seem to exist

Expression

• expressed in embryonic kidney, lung & placenta

More general terms

• matrilin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8785
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8785
• OMIM: https://mirror.omim.org/entry/603897
• UniProt: http://www.uniprot.org/uniprot/O95460.html