neuronal pentraxin-1; NP1; neuronal pentraxin I; NP-I (NPTX1)

Function

• may mediate uptake of degraded synaptic material
• may play a role in synaptic remodeling
• can mediate neuronal & glial uptake of the snake venom toxin taipoxin

Cofactor: binds 2 Ca+2 per subunit (putative)

Structure

contains 1 pentraxin domain

Compartment

cytoplasmic vesicle, secretory vesicle

More general terms

• pentraxin-2 (neuronal pentraxin, NPTX)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4884
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4884
• OMIM: https://mirror.omim.org/entry/602367
• UniProt: http://www.uniprot.org/uniprot/Q15818.html