nicotinic receptor beta-1; acetylcholine receptor subunit beta (CHRNB1, ACHRB, CHRNB)

Function

• nicotinic receptor beta subunit

Structure

• belongs to the ligand-gated ionic channel (TC 1.A.9) family

Compartment

• cell junction, synapse, postsynaptic cell membrane

Pathology

• defects in CHRNB1 are a cause of
  • congenital myasthenic syndrome slow-channel type
  • congenital myasthenic syndrome with acetylcholine receptor deficiency

More general terms

• nicotinic receptor beta subunit

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1140
• OMIM: https://mirror.omim.org/entry/100710
• OMIM: https://mirror.omim.org/entry/601462
• OMIM: https://mirror.omim.org/entry/608931
• UniProt: http://www.uniprot.org/uniprot/P11230.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1140