GTP-binding regulatory protein beta-2; transducin beta chain 2; (GNB2)
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Function
- G-beta & G-gamma chains are required for
- GTPase activity of heterotrimeric G proteins
- replacement of GDP by GTP
- G protein-effector interaction
- interacts with ARHGEF18
Structure
- G proteins are composed of 3 units G-alpha, G-beta & G-gamma
- belongs to the WD repeat G protein beta family
- contains 7 WD repeats
Expression
- nearly ubiquitously expressed
More general terms
Additional terms
References
- ↑ Simon MI, Strathmann MP, Gautam N. Diversity of G proteins in signal transduction. Science. 1991 May 10;252(5007):802-8. Review. PMID: https://www.ncbi.nlm.nih.gov/pubmed/1902986
- ↑ Hepler JR & Gilman AG G proteins TIBS 17:383 1992 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1455506
- ↑ UniProt http://www.uniprot.org/uniprot/P62879.html