carbonic anhydrase-3 (CA3)

Function

• reversible hydration of carbon dioxide

H2CO3 <--> CO2 + H2O

Cofactor: Zn+2 (putative)

Structure

belongs to the alpha-carbonic anhydrase family

Compartment

cytoplasm

Expression

• muscle specific
• at 6 weeks gestation, transcripts accumulate at low levels in somites & at high levels throughout the notochord, as gestation continues, CA3 becomes abundant in all developing muscle masses & continues at high to moderate levels in the notochord

More general terms

• carbonic anhydrase (dehydratase)

Database

• UniProt: http://www.uniprot.org/uniprot/P07451.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:761
• OMIM: https://mirror.omim.org/entry/114750
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=761