nanos homolog 2 (NANOS2, NOS2)

Function

• required to support proliferation & self-renewal of proximal germ cells in males only
• translational repression of specific mRNAs by associating with the 3' untranslated regions of mRNA targets via nanos-type zinc finger (putative)
• essential for spermatogonia formation

Structure

• contains 1 nanos-type zinc finger

More general terms

• zinc finger protein

Database

• OMIM: https://mirror.omim.org/entry/608228
• UniProt: http://www.uniprot.org/uniprot/P60321.html